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Sometime during the course of human evolution, a side-branch of mutants emerged who called themselves the Neo. They are regular mutants who decided to live reclusively, waiting for humanity to self-annihilate so the Neo could inherit the Earth.

The were content living a solitary life in their community until the X-Gene was "shut off" and several Neo mutants died. The Neo who survived swore vengeance on the X-Men, despite it not actually being caused by the X-Men.

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